Complex Mixture Analysis (UPLC/Quadrupole MS) eLearning Track
This track contains 10 modules that covers information necessary to perform complex mixture analysis on a UPLC/Quadrupole MS system. Topics include fundamentals of LCMS, MassLynx fundamentals, Intellistart, Positive and ChromaLynx application manager. It also contains additional information in regards to controlling contamination.
If you would like to register for individual eLearning courses, please see courses below:
750000690 - Fundamentals of LCMS
This module will explain the Fundamental Concepts that will build a foundation for your understanding of the more complex, instrument-specific information that you will see in other modules.
750000691 - Basic MassLynx Functions
This course is designed to give new users a fundamental understanding of the software architecture, basic functions and the tools present in MassLynx v4.1.
750001018 - Controlling Contamination in LC and LCMS Systems : Part 1
This module covers best practices for controlling contamination in LC and LCMS systems. Topics include common definitions, tips on preventing contamination and solvent considerations.
750001019 - Controlling Contamination in LC and LCMS Systems : Part 2
This module covers best practices for controlling contamination in LC and LCMS systems. Topics include troubleshooting, sources of contamination and cleaning procedures to mitigate contamination.
750000658 - Binary vs. Quaternary Gradient Systems
This module discusses two types of solvent delivery systems; binary versus quaternary gradient systems. It reviews the similarities and differences between the two systems and how to optimize for UPLC gradient chromatography. The topics covered include hardware components, gradient formation, specification differences, system volume and re-equilibration considerations.
750000692 - Intellistart: Quadrupole-Based MS Systems
This eLearning module introduces the user to the powerful, automated capabilities of Intellistart for quadrupole LC/MS systems. These include Resolution Setup, m/z Calibration, Sample Tune, and the LC/MS System Check. In addition, the influence of quadrupole resolving power on ion transmission and method robustness are discussed, along with the ability of Intellistart to create MS acquisition methods.
750000702 - ChromaLynx – Non-Targeted Analysis
ChromaLynx XS facilitates the identification of compounds in complex mixtures by utilizing automated chromatographic peak detection, mass spectral deconvolution, library searching, accurate mass measurements, and rigorous sample comparison algorithms. Module 1 focuses on nontargeted analysis and the Compare functionality. Processing methods are developed along with navigational guidance through the ChromaLynx XS browser for maximum visualization of the processed data.
750000703 - ChromaLynx – Targeted Screening
This module focuses on targeted analysis including fragment ion confirmation. Processing methods are developed along with navigational guidance through the ChromaLynx XS browser.
750000704 - ChromaLynx Libraries
This module demonstrates how to create a MassLynx library and convert it to a NIST library for use with ChromaLynx.