OVERVIEW

Synthetic oligonucleotide therapeutics require thorough analysis to establish purity, identity, and quality. As sequence length, chemical modifications, and regulatory expectations increase, so does the need for robust, reliable analytical methods. This educational seminar highlights complete workflows from separation to detection and analyzing your data with high quality optimized specifically for synthetic oligonucleotide analysis.

AGENDA

  • Fundamentals of Ion-Pairing Reverse Phase Separation of Oligonucleotides- Introduction to New 1mm I.D microflow column solutions for improved resolution and sensitivity
  • Orthogonal techniques (HILIC, AEX, SEC) for oligonucleotide comprehensive profiling.
  • Sequence to Impurities: In-depth Oligonucleotide Characterization Using Next-Generation Multi-Reflecting TOF Mass Spectrometry
  • High-throughput method development for identity and impurity screening of synthetic oligonucleotides using the BioAccord System; accessible to users of all levels of LC-MS Experience

LAB DEMO:

  1. Learn how to automate your routine pipetting steps to improve reproducibility and throughput in oligo workflows- Andrew+ Pipetting Robot.
  2. Simplify your Oligo LC-MS Analysis with the BioAccord™ System and Waters Connect™ Informatics.

Don’t miss this opportunity to stay ahead in science behind oligonucleotide analysis! 

Reserve your spot now!

 

 April 8th, 2026
9:00am-3:00pm EST

Immerse Cambridge
301 Binney St. Suite 102 
Cambridge, MA 02142


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Event Cancelled
April 30th, 2026

9:00am-3:00pm PT

Address: 155 N.
McCarthy Blvd.

Milpitas, CA 95035

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 April 9th, 2026
9:00am-3:00pm EST

Waters Corporation
5 Tech Dr, Building A, Room C4
Milford, MA 07924

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May 5th, 2026
9:00am-3:00pm PT

Hilton Bellevue
300 112th Avenue SE,
Bellevue, WA 98004

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April 29th, 2026
9:00am-3:00pm EST

11202 El Camino Real,
Room no: 11202

San Diego, CA, 92130

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 May 6th, 2026
9:00am-3:00pm PT

16341 Table Mountain Pkwy,
Golden, CO 80403

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Questions? Additional information? Contact: Ravali_alagandula@waters.com