Crystallization: Mastering Seeded Antisolvent Techniques

Crystallization plays a pivotal role in the production of high-quality specialty bulk products. This process will influence particle size, purity, and product yield all while needing to be monitored and controlled to meet a product’s specifications. This 3-hour fully accredited training is tailored for process chemists, chemical engineers, and pharmaceutical engineers. It delves into the critical role of crystallization, focusing specifically on seeded anti-solvent crystallization processes. Participants will explore the challenges encountered in industries such as pharmaceuticals, food, fine chemicals, and cosmetics. Through immersive case studies and practical demonstrations, attendees will gain a comprehensive understanding of advanced techniques in seeded anti-solvent crystallization. Topics covered include fundamental principles, phase diagrams, and innovative seeding strategies. Emphasis will be placed on mastering supersaturation generation and control, diverse seeding methodologies, and cutting-edge in-situ seed bed formation techniques. Additionally, participants will tackle the complexities of scaling up processes, overcoming challenges related to local effects and mixing regimes during scale up operation, ensuring safety. By the end of the course, process chemists, chemical engineers, and pharmaceutical engineers will be equipped to navigate seeded anti-solvent crystallization processes effectively, contributing to the efficient and consistent production of large-scale crystallized products with defined physical properties.