Complex Mixture Analysis (UPLC/QTOF MS) eLearning Track

This track contains 12 modules that covers information necessary to perform complex mixture analysis on a UPLC/QTOF MS system. Topics include fundamentals of LCMS, MassLynx fundamentals, Intellistart, Elemental Composition MSe Viewer, Positive and ChromaLynx application manager.  It also contains additional information in regards to controlling contamination.

If you would like to register for individual eLearning courses, please see courses below:

750000690 - Fundamentals of LCMS
This module will explain the Fundamental Concepts that will build a foundation for your understanding of the more complex, instrument-specific information that you will see in other modules.


750000691 - Basic MassLynx Functions
This course is designed to give new users a fundamental understanding of the software architecture, basic functions and the tools present in MassLynx v4.1.

750001018 - Controlling Contamination in LC and LCMS Systems : Part 1
This module covers best practices for controlling contamination in LC and LCMS systems. Topics include common definitions, tips on preventing contamination and solvent considerations.

750001019 - Controlling Contamination in LC and LCMS Systems : Part 2
This module covers best practices for controlling contamination in LC and LCMS systems. Topics include troubleshooting, sources of contamination and cleaning procedures to mitigate contamination.

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750000658 - Binary vs. Quaternary Gradient Systems
This module discusses two types of solvent delivery systems; binary versus quaternary gradient systems.  It reviews the similarities and differences between the two systems and how to optimize for UPLC gradient chromatography.  The topics covered include hardware components, gradient formation, specification differences, system volume and re-equilibration considerations.

750000693 - Intellistart: QTOF-Based MS Systems
This eLearning module introduces the user to the powerful, automated capabilities of Intellistart for time-of-flight LC/MS systems. These include optimizing the detector voltage, calibrating the m/z axis, and setting up the lockspray conditions. In addition, the module covers Intellistart operations which monitor mass measurement accuracy and optimal LC/MS system performance.

750000695 - Elemental Composition
This eLearning module describes how to use Elemental composition to obtain the chemical formula of unknowns using accurate mass data.


750000702 - ChromaLynx – Non-Targeted Analysis
ChromaLynx XS facilitates the identification of compounds in complex mixtures by utilizing automated chromatographic peak detection, mass spectral deconvolution, library searching, accurate mass measurements, and rigorous sample comparison algorithms.  Module 1 focuses on nontargeted analysis and the Compare functionality.  Processing methods are developed along with navigational guidance through the ChromaLynx XS browser for maximum visualization of the processed data.

750000703 - ChromaLynx – Targeted Screening
This module focuses on targeted analysis including fragment ion confirmation. Processing methods are developed along with navigational guidance through the ChromaLynx XS browser.