MassLynx Time of Flight Core eLearning Track
This track contains 25 modules and covers theory and operation of MassLynx controlled Time-of-Flight (TOF)-based LC/MS systems. This track covers theoretical and practical aspects of LC method development, LC and MS instrument set up/control and basic analysis of LC/MS data.
If you would like to register for individual eLearning courses, please see courses below:
750001018 Controlling Contamination in LC and LCMS Systems : Part 1
This module covers best practices for controlling contamination in LC and LCMS systems. Topics include common definitions, tips on preventing contamination and solvent considerations.
750001019 Controlling Contamination in LC and LCMS Systems : Part 2
This module covers best practices for controlling contamination in LC and LCMS systems. Topics include troubleshooting, sources of contamination and cleaning procedures to mitigate contamination.
750000658 Binary vs. Quaternary Gradient Systems
This module discusses two types of solvent delivery systems; binary versus quaternary gradient systems. It reviews the similarities and differences between the two systems and how to optimize for UPLC gradient chromatography. The topics covered include hardware components, gradient formation, specification differences, system volume and re-equilibration considerations.
750000787 UPLC Sample Injection Modes
This module will discuss two types of sample injection: Fixed Loop and Flow Through Needle. The topics to be covered include the injection and wash cycles, the advantages of the different injection modes, how to optimize peak area reproducibility and how to minimize carryover.
750000788 Achieving the Best LC Peak Shape
Good peak shape is crucial in liquid chromatography for the best sensitivity, peak resolution, and reproducibility of peak areas and retention times. Causes of non-ideal peak shapes and how to improve peak shape are discussed.
750000844 ACQUITY Tips and Techniques
Tips and techniques for the proper set up, preparation, running and shutting down of an ACQUITY system are discussed, along with the use of the ACQUITY Console for system evaluation. The process and tools for the migration of HPLC methods to UPLC methods is presented.
750000988 HPLC and UPLC Best Practices and Troubleshooting
This module will cover best practices for HPLC and UPLC users to optimize performance and maximize up-time of the system. The module focuses on prevention and troubleshooting of common LC problems.
750000663 LC Method Development
This module is designed to provide a fundamental understanding of LC method development techniques.
750000773 Practical Tips for UV and PDA Detection
This module will discuss practical tips for optimizing Tunable UV (TUV) and Photodiode Array (PDA) detectors for maximum linearity and sensitivity, rugged and reproducible methods.
750000659 LC/MS Contamination Issues
This course will discuss how to minimize contamination in LC/MS. It defines what contamination is, where it comes from, with examples, how it can affect your chromatography and spectra, and how to minimize it.
750000660 LC/MS Introduction
This module is designed to introduce the basics of mass measurement and establish the foundation for topics presented in later modules.
750000661 Ionization Modes
The three most common modes of ionization in LC/MS are presented in this module: electrospray, atmospheric pressure chemical ionization (APCI), and atmospheric pressure photo ionization (APPI).
750000662 Mass Analyzers
The most common mass analyzers present in current LC/MS instruments are presented in this module: single and tandem quadrupole, time of flight and ion trap.
750000690 Fundamentals of LCMS
This module will explain the Fundamental Concepts that will build a foundation for your understanding of the more complex, instrument-specific information that you will see in other modules.
750000912 Basic Tuning and Calibration for LCMS TOF-Based Systems
Basic tuning and calibration familiarization for new LCMS TOF users. This module covers set up of the Xevo G2-XS QTOF mass spectrometer using IntelliStart; includes detector set up, calibration and lockspray set up.
750000913 Basic LC Method Familiarization for LCMS TOF-Based Systems
Basic LC method familiarization for new LCMS TOF users. This module covers basic set up of the ACQUITY system for use with a Xevo G2-XS QTOF mass spectrometer; includes the gradient table and sample manager parameters.
750000914 Basic MS Methods for LCMS TOF-Based Systems
Basic MS method familiarization for new LCMS TOF users. This module covers basic set up of MS and MSe methods for use with a Xevo G2-XS QTOF mass spectrometer.
750000693 Intellistart - QTOF Based MS Systems
This eLearning module introduces the user to the powerful, automated capabilities of Intellistart for time-of-flight LC/MS systems. These include optimizing the detector voltage, calibrating the m/z axis, and setting up the lockspray conditions. In addition, the module covers Intellistart operations which monitor mass measurement accuracy and optimal LC/MS system performance.
750000691 Basic MassLynx Functions
This course is designed to give new users a fundamental understanding of the software architecture, basic functions and the tools present in MassLynx v4.1.
750000695 Elemental Composition
This eLearning module describes how to use Elemental composition to obtain the chemical formula of unknowns using accurate mass data.
750000709 MassLynx - Architecture
This module will show the basic structure of MassLynx and how to navigate the main page to locate Instrument controls and useful tools.
750000710 MassLynx - Data Acquisition
This module will show you how to create a simple sample list for data acquisition.
750000711 MassLynx Data Processing and Review - Chromatogram Window
The Chromatogram window is the primary MassLynx tool used to interact with a chromatogram. This module will show you the more common user performed tasks in the Chromatogram window. Topics range from basic display options to chromatogram integration.
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750000712 MassLynx Data Processing and Review - Spectrum
The Spectrum window is the primary MassLynx tool used to interact with mass spectra. This module will show you the more common user performed tasks in the Spectrum window. Additionally, some MassLynx spectrum tools are shown.
750000713 MassLynx Data Processing - Strip Functions
The MassLynx Strip functions provide a way of removing noise and unwanted information in a .raw data file.